IDEC Pharmaceuticals Corporation

IDEC Pharmaceuticals Corporation
IDEC Pharmaceuticals Corporation

Formulation Buffer

NFPA

0
0 0

MSDS Name: Formulation Buffer
Manufacturer Name: IDEC Pharmaceuticals Corporation
Address:
3030 Callan Road,
San Diego, California 92121

General Information Number:
M-F, 9-5 West Coast Hours: (858) 431-8822
Business Phone: (858) 431-8500
Business Fax: (858) 431-8750
For information in North America, call: (858) 431-8500
Chemtrec: For emergencies in the US, call CHEMTREC: 800-424-9300
Manufacturer MSDS Revision Date: 2/29/00
Trade Names:
Formulation Buffer
US Adopted Name/INW:
Not established as of the date of issuance of this MSDS.

Other Name: Not established as of the date of issuance of this MSDS.

Chemical Name: Not established as of the date of issuance of this MSDS.

Note: The following information is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. This safety data sheet is not intended to be a substitute for product literature which may accompany the finished product.

NFPA

Health: 0
Flammability: 0
Reactivity: 0
Other:


Product Codes:
120015
Other Exposure Guidelines:
None established

Formulation: 7.5 mg/mL
Chemical Name
DTPA
CAS#
67-43-6
Other Exposure Guidelines:
None established

Formulation: 0.5 mg/mL
Chemical Name
Phosphate Buffered Saline
CAS#
Not Applicable
Other Exposure Guidelines:
None established

Formulation: Proprietary
Chemical Name
Water-for-Injection
CAS#
Not Applicable
Other Exposure Guidelines:
None established

Formulation: Proprietary
SECTION 3 : HAZARDS IDENTIFICATION
Potential Health Effects:
This material may be irritating to eyes, respiratory system and skin.
This material is not readily absorbed through skin.

National Fire Prevention Association Ratings:
Health = 0
Fire = 0
Reactivity = 0
SECTION 4 : FIRST AID MEASURES
Eye Contact:
In case of contact with eyes flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Consult a physician.
Skin Contact:
In case of skin contact, flush with copious amounts of water while removing contaminated clothing. Consult a physician.
Inhalation:
If inhaled, move to fresh air. If breathing becomes difficult consult a physician.
Ingestion:
If swallowed, wash out mouth with water provided that the person is conscious. Consult a physician.
SECTION 5 : FIRE FIGHTING MEASURES
Flash Point:
None established.
Upper Flammable or Explosive Limit:
None established.
Lower Flammable or Explosive Limit:
None established.
Extinguishing Media:
Use extinguishing media appropriate to surrounding fire conditions

Will not burn.
Hazardous Combustion Byproducts:
Material is non-combustible.
Unusual Fire Hazards:
None
SECTION 6 : ACCIDENTAL RELEASE MEASURES
Personal Precautions:
The use of gloves, lab coats, and eye protection are always recommended when dealing with a chemical spill or a leaking chemical container.
Spill Cleanup Measures:
Contaminated items generated during spill clean-up should be disposed of in accordance with internal guidelines regarding chemical/pharmaceutical waste.
SECTION 7 : HANDLING and STORAGE
Storage:
Vials of formulation buffer are stable at 2 to 8 deg C (36 to 46 deg F). Vials should be protected from direct sunlight. Discard any unused portion left in the vial.
SECTION 8 : EXPOSURE CONTROLS, PERSONAL PROTECTION
Hand Protection Description:
The use of eye protection is always recommended when working with these or any other chemical reagents.
Eye/Face Protection:
The use of gloves, is always recommended when working with these or any other chemical reagents.
Protective Clothing/Body Protection:
The use of lab coats is always recommended when working with these or any other chemical reagents.
SECTION 9 : PHYSICAL AND CHEMICAL PROPERTIES
Physical State/Appearance:
Formulation buffer is clear, liquid.
Color:
Yellow to amber
pH:
7.2
Solubility:
Material is water soluble.
Specific Gravity:
Unknown
Flashpoint:
None established.
Upper Flammable Explosive Limit:
None established.
Lower Flammable Explosive Limit:
None established.

Extinguish Media: Will not burn.
Unusual Fire/Explosion Hazards: None
SECTION 10 : STABILITY AND REACTIVITY
Incompatibilities with Other Materials:
Chemically stable.
Hazardous Polymerization:
Will not occur.
Hazardous Decomposition Products:
No dangerous decomposition products known.
SECTION 11 : TOXICOLOGICAL INFORMATION
Applies to all ingredients:
Acute Health Effects:
Formulation buffer is formulated for intravenous administration. The toxicological effects of this substance have not been thoroughly investigated.
Chronic Effects:
No data available at this time.
Carcinogenicity:
No long term studies have been performed to establish the carcinogenicity potential of the formulation buffer.
Mutagenicity:
No long term studies have been performed to establish the mutagenic potential of the formulation buffer.
Other Toxicological Information:
Impairment of Fertility: No long term studies have been performed to determine its effects on fertility in males or females.
DTPA:
Other Toxicological Information:
Information provided by SIGMA in their Material Safety Data Sheet for DTPA indicates that DTPA may contain trace amounts of nitrilotriacetic acid (CAS # 139-13-9), a chemical known to the state of California to cause cancer and/or birth defects or reproductive harm.
SECTION 12 : ECOLOGICAL INFORMATION
Ecological Paragraph:
Neither the formulation buffer nor any of its ingredients are listed as marine pollutants.
SECTION 13 : DISPOSAL CONSIDERATIONS
Waste Disposal:
Dispose of waste material in accordance with all applicable environmental laws.

This material may be burned in a chemical incinerator equipped with an afterburner and scrubber.
SECTION 14 : TRANSPORT INFORMATION
Transportation Information:
No data available at this time.
SECTION 15 : REGULATORY INFORMATION
Applies to all ingredients:
European Community Chemical Inventory Status:
Formulation buffer is not subject to classification and labeling according to EU Directive 92/32/EEC.
SECTION 16 : ADDITIONAL INFORMATION
NFPA:
Fire Hazard: 0
Health: 0
Reactivity: 0
MSDS Revision Date:
2/29/00
MSDS Author:
Department Issuing MSDS: Environmental Health and Safety.
Disclaimer:
As of the date of issuance, we are providing available information relevant to the handling of this material in the workplace. All information contained herein is offered in good faith belief that it is accurate. However, this safety data sheet does not constitute a warranty of any kind, express or implied. In the event of an adverse incident associated with this material, this safety data sheet is not, and is not intended to be, a substitute for consultation with appropriately trained personnel.

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